Publications – ABC Lab

Blokhina Y, Buchwalter A. Modeling the consequences of age-linked ribosomal DNA hypermethylation with dCas9-directed DNA methylation in human cells. BioRXiV 2023.

Buchwalter A. Intermediate, but not average: the unusual lives of the nuclear lamin proteins. Current Opinion in Cell Biology 2023. PDF

Hasper J, Welle K, Swovick K, Hryhorenko J, Ghaemmaghami S, Buchwalter A. Long lifetime and selective accumulation of lamin A/C in Hutchinson-Gilford progeria syndrome. BioRXiV 2023 / in press at Journal of Cell Biology

Hasper J, Welle K, Hryhorenko J, Ghaemmaghami S, Buchwalter A. Turnover and replication analysis by isotope labeling (TRAIL) reveals the influence of tissue context on protein and organelle lifetimes. Molecular Systems Biology 2023. PDF

Blokhina Y, Buchwalter A. Moving fast and breaking things: incidence and repair of DNA damage within ribosomal DNA repeats. Mutat Res 2020 May-Dec 2020. PDF

Publications – AB 

Buchwalter A*, Schulte R, Tsai H, Capitanio J, Hetzer MW*. Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress. eLife 2019 Oct 10. *co-corresponding authors. PDF

Buchwalter A, Kaneshiro JM, Hetzer MW. Coaching from the sidelines: the nuclear periphery in genome organization. Nature Reviews Genetics 2018 Oct 24. PDF

Buchwalter A, Hetzer MW. Nucleolar expansion and elevated protein translation in premature aging. Nature Communications 2017 Aug 30;8(1):328. PDF

Goodchild R, Buchwalter A, Naismith TV, Holbrook K, Billion K, Dauer WT, Liang C-C, Dear ML, Hanson PI. Access of torsinA to the inner nuclear membrane is activity dependent and regulated in the endoplasmic reticulum. Journal of Cell Science 2015 Aug 1;128(15):2854-65. PDF

Buchwalter A, Liang Y, Hetzer MW. Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics. Molecular Biology of the Cell 2014 Aug 15;25(16):2472-84. PDF

Vander Heyden AB, Naismith TC, Snapp EL, Hanson PI. Static retention of the lumenal monotopic membrane protein torsinA in the endoplasmic reticulum. EMBO Journal 2011 Jul 22;30(16):3217-31. PDF

Vander Heyden AB, Naismith TV, Snapp EL, Hodzic D, Hanson PI. LULL1 retargets torsinA to the nuclear envelope revealing an activity that is impaired by the DYT1 dystonia mutation. Molecular Biology of the Cell 2009 Jun 1;20(11):2661-2672. PDF