Publications – ABC Lab
Research Articles
Marin H, Simental E, Allen C, Martin E, Panning B, Al-Sady B, Buchwalter A. The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate. BioRXiV 2024.
Hasper J, Welle K, Swovick K, Hryhorenko J, Ghaemmaghami S, Buchwalter A. Long lifetime and selective accumulation of lamin A/C in Hutchinson-Gilford progeria syndrome. Journal of Cell Biology 2024. PDF
Blokhina Y, Buchwalter A. Modeling the consequences of age-linked ribosomal DNA hypermethylation with dCas9-directed DNA methylation in human cells. BioRXiV 2023.
Hasper J, Welle K, Hryhorenko J, Ghaemmaghami S, Buchwalter A. Turnover and replication analysis by isotope labeling (TRAIL) reveals the influence of tissue context on protein and organelle lifetimes. Molecular Systems Biology 2023. PDF
Reviews + Perspectives
Buchwalter A. What does it take to build a nucleus? Nature Reviews Molecular Cell Biology 2024. PDF
Buchwalter A. Intermediate, but not average: the unusual lives of the nuclear lamin proteins. Current Opinion in Cell Biology 2023. PDF
Blokhina Y, Buchwalter A. Moving fast and breaking things: incidence and repair of DNA damage within ribosomal DNA repeats. Mutat Res 2020. PDF
Publications – AB
Buchwalter A*, Schulte R, Tsai H, Capitanio J, Hetzer MW*. Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress. eLife 2019 Oct 10. *co-corresponding authors. PDF
Buchwalter A, Kaneshiro JM, Hetzer MW. Coaching from the sidelines: the nuclear periphery in genome organization. Nature Reviews Genetics 2018 Oct 24. PDF
Buchwalter A, Hetzer MW. Nucleolar expansion and elevated protein translation in premature aging. Nature Communications 2017 Aug 30;8(1):328. PDF
Goodchild R, Buchwalter A, Naismith TV, Holbrook K, Billion K, Dauer WT, Liang C-C, Dear ML, Hanson PI. Access of torsinA to the inner nuclear membrane is activity dependent and regulated in the endoplasmic reticulum. Journal of Cell Science 2015 Aug 1;128(15):2854-65. PDF
Buchwalter A, Liang Y, Hetzer MW. Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics. Molecular Biology of the Cell 2014 Aug 15;25(16):2472-84. PDF
Vander Heyden AB, Naismith TC, Snapp EL, Hanson PI. Static retention of the lumenal monotopic membrane protein torsinA in the endoplasmic reticulum. EMBO Journal 2011 Jul 22;30(16):3217-31. PDF
Vander Heyden AB, Naismith TV, Snapp EL, Hodzic D, Hanson PI. LULL1 retargets torsinA to the nuclear envelope revealing an activity that is impaired by the DYT1 dystonia mutation. Molecular Biology of the Cell 2009 Jun 1;20(11):2661-2672. PDF